Amidst the many science experiments conducted in the series, one of the most controversial, and essentially interesting of them all was the Senku Cola. The Senku Cola was originally made by Senku in an attempt to get Gen to side with him, and well, needless to say, it was a success. Now during that time, there were limited ingredients, and not much can actually be done, but the mind of the scientist fails at no time, and after much digging, Senku finally made cola out of four ingredients: Lime (with the rind), Cilantro, Caramel, and Carbonated Water.
Senku Cola is present post-creation in both the manga and anime, and the spectator is given a list of ingredients: lime (including the rind), cilantro, caramel created from burning honey, and carbonated water. As a result, the easily available resources have become cannon fodder for experimentation, ushering in a new era of culinary exploration. The process of preparation is debatable.
How to Make the Cola Recipe From Dr. Stone

Fans have raced to the kitchen to try to reproduce a bit of the year 5739 in their own homes, and two main preparation methods have emerged. The first way, known as the “mix-it-up!” method, is the easier of the two. This approach simply combines the ingredients in a glass and stirs until they are uniform in consistency. It’s simple, it’s not always delicious, and it’s tempting to skip the caramelization phase and just use plain honey instead.
The Senku-cola may seem like an easy recipe that could be done in any kitchen, but every fan who’s ever tried making it is having a hard time adjusting the recipe so it could be just right. As Senku always says, science is an everyday process of learning, and you must not be afraid of failing, but never forget to try and try again until you get the recipe just right (maybe even you could lure Gen into joining your team).